High-dose antiangiogenic therapy for glioblastoma: less may be more?
نویسنده
چکیده
Targeting angiogenesis in glioblastoma rapidly reduces vascular permeability and contrast enhancement on MRI and prolongs progression-free survival. The long-term efficacy of bevacizumab and other antiangiogenic agents is limited, however, because of the rapid development of resistance. Alternative dosing approaches may be one mechanism of prolonging therapeutic efficacy.
منابع مشابه
High-Dose Antiangiogenic Therapy for Glioblastoma: Less May Be More?
John F. de Groot Author’s Affiliations: Brain Tumor Center and Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX Running Title: Dosing effects of antiangiogenic therapy in glioblastoma
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عنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 17 19 شماره
صفحات -
تاریخ انتشار 2011